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To maintain the benefits over time, you'll need maintenance sessions and healthy lifestyle choices

Pharmacokinetic comparisons between diabetic individuals and healthy individuals have shown that tirzepatide delays gastric emptying, particularly after a single dose, and demonstrates a decrease in effectiveness or responsiveness with repeated once-weekly dosing, referred to as tachyphylaxis [44, 72]

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If you have risk factors or these symptoms, your doctor may recommend testing for vitamin B12 deficiency