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OASIS 1 was a double-blind, randomized, controlled, phase 3 superiority trial in which investigators assessed the efficacy and safety of a 68-week treatment with the once-daily oral GLP-1 analog semaglutide versus placebo for overweight or obesity in adults without type 2 diabetes

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387 2 2.5mg1INJE800021,10011 3 3mg6RYBE350028,02755011 SNS GLP-1 GLP-1 GLP-1 GLP-1 vs BMI BMI 5 5 3 3 / GLP-1 1130 7,00015,000 1GIPGLP-12 11 25,00050,00020,00040,000 SGLT2 GLP-1 SGLT2 1200400kcal Canagliflozin: A Novel SGLT2 Inhibitor for Type 2 Diabetes Mellitus 10,00015,000 UP 5,00010,000 5 1 GLP-1 3 12 1 4 4 22 3 3 3 3mg6RYBE350028,02755011 RYBE35001,650 5,420GLP-13mg217,92045,020r73b7 OK 15%OFF OK RYBE3500 1 2 RYBE35001,650 3 3mg6RYBE350028,02755011 DMM DMM 0 DMM 0 r73b7 DMM +1,50023248002000 5,420r73b71GLP-13mg217,92045,020 DMMDMH DMM DMM DMM 8 2 OK 15 0 11 3mg7mg LINEIT 3mg27mg NG 2 ICU FAQ 2 5kg 1 13

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doi:10.1152/ajpendo.1997.273.5.E981 13

It contributes to the normal functioning of the immune system