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Primary outcomes included changes in TTR, INR, and INR recheck frequency

Another obstacle in the healing process of chronic diabetic wounds is the infiltration of M1-phenotype macrophages

They tested these inhibitors in cell and animal models. They reported changes in intracellular nicotinamide-related metabolites and examined the biological effects of NNMT inhibition under experimental conditions. These outcomes have increased scientific interest in NNMT biology

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Li R, Lin W, Kuang Y, Wang J, Xu S, Shen C, Qiu Q, Shi M, Xiao Y, Liang L, Xu H