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There have been rare post marketing reports of pulmonary aspiration in patients receiving GLP-1 receptor agonists undergoing elective surgeries or procedures requiring general anesthesia or deep sedation who had residual gastric contents despite reported adherence to preoperative fasting recommendations

In a trial comparing Xultophy to basal-bolus therapy, participants were much more likely to improve glycemic control with Xultophy

Regular or heavy alcohol consumption can interfere with the body's ability to absorb Vitamin B12 from the gut, making the supplement less effective