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Oxalate inhibits kidney epithelial cell proliferation, promotes fibrotic transformation, calcification and atherosclerosis, and induces cell death
Interestingly, such signs of mitochondrial dysfunction have also been described in MDD and long COVID: de Boer et al
Antioxidant categories and mode of action
PDIA4 targets IRE1/sXBP1 to alleviate NLRP3 inflammasome activation and renal tubular injury in diabetic kidney disease
5oq and Extended Data Fig
Because GSH rapidly oxidizes outside cells, variables like collection time, processing delays, temperature, and anticoagulants significantly affect accurate measurement, particularly in the unstable reduced fraction of GSH [118]
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