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In addition, the predominant intracellular localization of metabolizing enzymes required for the release of the parent drug from prodrugs (Table II) supports the utilization of the prodrug approach for drugs with intracellular targets

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In a 4-week study of rhIGF-1 in healthy adults, mean 24-hour GH pulsatility decreased by approximately 50% compared with baseline, with partial recovery after cessation [18]

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[PMID: 38206684] PubMed record related to this compound for laboratory literature review