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The multivariate Cox proportional hazards model was used to explore independent prognostic predictors for the overall survival of patients with breast cancer
Forcina, L., Miano, C., Scicchitano, B
Unlike prior studies emphasizing single-organ effects, our analysis reveals that ferroptosis drives a self-reinforcing cycle: Hyperglycemia in DM triggers systemic iron overload, and the accumulation of iron in peripheral organs, combined with oxidative stress imbalance, causes organ damage (including pancreatic -cells), further exacerbating the progression of DM and forming a pathological feedback loop
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However, if you have a sensitive stomach, taking them with a light meal is perfectly fine