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Short answer: Yes when done correctly and under medical supervision

"Metabolism and DNA binding studies of 4-hydroxyestradiol and estradiol-3,4-quinone in vitro and in female ACI rat mammary gland in vivo"

A peer-reviewed clinical study in the Journal of Sexual Medicine demonstrating that growth hormone secretagogue treatment in hypogonadal men raises serum IGF-1 levels and improves body composition markers illustrates the kind of measurable but moderate effects that the GHRH-pathway peptides produce when used correctly