Although never fully embraced by the medical community (Phelan et al., 2015
Some researchers choose even longer intervals, spending 6 to 8 weeks at each dose level, particularly if they notice heart rate increases above 10 beats per minute from baseline
Figure 2 Exposure to GA agents ISO (56), SEV (57), PPF (58) and KET (5961) have consistently been demonstrated to result in fragmented mitochondrial phenotypes with in vitro exposures to neurons in human (58, 59, 61), rat (56), and mouse (57) models
Following a thorough examination, outliers were excluded before subsequent analysis
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Patients who are pregnant or breastfeeding, have active cancer or a recent cancer history, or are on immunosuppressive medication should not use KPV