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The search for infectious causes of human cancers: where and why
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T., Lin, G., Wu, P
There are marked decreases in the editing of the AMPAR GluA2 subunit and increases in the expression of GluA1 subunits in human GBM samples and cell lines (Maas et al., 2001
however, various factors may deplete it, including stress, aging, pollution, and long-term medical conditions
Apart from intrinsic signaling, the TME shapes CSCs behavior and mechanical cures from ECM further modulates CSC fate, with poor stiffness enhancing stemness and high stress leading to quiescence via distinct integrin-dependent pathways
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