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If side effects are problematic, your doctor can discuss alternatives, including: Dose adjustment or slower titration Switching to a different GLP-1 receptor agonist Alternative diabetes medications with different mechanisms of action Additional treatments to manage specific symptoms According to NICE guidance on type 2 diabetes management (NG28), treatment decisions should be individualised, balancing efficacy, side effects, patient preferences, and overall quality of life

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l-carnitine could also protect against SARS-CoV-2-induced cardiotoxicity resulting from dysregulated ACE2 signaling pathway 637,638

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In fact, for most of us, making adjustments to increase GLP-1 naturallyeven if those changes are smallwill help us get to where we need to be