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Psoriatic arthritis (PA) is an autoimmune disorder that causes inflammation in the joints and skin , leading to pain, stiffness, swelling, and reduced mobility

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They can block pro-inflammatory signals like TNF or interleukin pathways by competing for receptor binding

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Although the higher dose of acetyl-l-carnitine did not improve survival (adjusted odds ratio [aOR] 1.18, 95% CI 0.463.02), the lower dose did (aOR 0.27, 95% CI 0.100.71)

The recommended dose for vitamin B12 may vary depending on specific medical conditions and the disease severity