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Genetics also plays a real role in how pronounced it becomes

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Therefore, combining fosphenytoin and lacosamide may increase toxicity without providing significant improvement in efficacy

PET studies suggest dysfunction in the thalamocortical pathways in patients with chronic migraine, potentially contributing to migraine chronicity (34)

10.1038/s41598-018-31353-1 79 WangY.WangH.HowardA