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(2) The Human Evidence Gap No completed, peer-reviewed Phase II or Phase III randomized controlled trials in humans have been published as of July 2025
As well as stimulating insulin release, GLP-1R agonists promote satiety and reduce food intake, leading to weight loss
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People taking GLP-1 medications had higher risks for 19 health outcomes, mostly involving digestive issues such as heartburn, nausea, vomiting, stomach pain and gastroparesis (stomach paralysis)
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Green tea catechins, for example, have been shown to modestly increase thermogenesis and fat oxidation in controlled settings
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