In order to do so, the pharmaceutical manufacturing company of the Generic Drug conducts stringent scientific studies (called BioEquivalence / BioAvailability Studies ) on Human Volunteers to test that the medicines have similar biological values like Absorption, Distribution, Metabolism And Excretion
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Evening dosing aligns with the bodys natural growth hormone rhythm, as the largest secretion pulses normally occur during deep sleep
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J Pharmacol Exp Ther 328(3):866-72, 2009
However, it may indirectly affect thyroid levels, especially for people with hypothyroidism