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To maintain homeostasis, organisms and cells developed a sophisticated enzymatic and non-enzymatic antioxidant defense system including catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx) that counteracts excessive ROS levels

Regulation of gamma-glutamycystein synthetase b-nonallosteric feedback inhibition by glutathione

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When GLP-1 signaling is activated in these areas, the perceived reward value of alcohol and other substances may decrease

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