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Neurochem Res 46:2333

Simultaneously, physical activity initiates mitochondrial biogenesis (mediated by peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PGC-1), enhances mitophagy, maintains the balance between mitochondrial fusion and fission, and optimizes electron transport chain efficiency, which collectively mitigates ROS production and safeguards the functionality of both muscle and endothelial cells (74)

Metabolic impact of glucagon deficiency

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