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Long-term safety, tolerability, and weight loss associated with metformin in the Diabetes Prevention Program Outcomes Study

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Important safety note for people with diabetes: If you are taking insulin or a sulfonylurea alongside any investigational glucose-lowering therapy, improvements in blood glucose control may increase the risk of hypoglycaemia

Efficacy in Glycemic Control: A Head-to-Head Comparison Semaglutide: Clinical trials, including the SUSTAIN and PIONEER studies, have showcased semaglutides prowess in achieving and maintaining glycemic control

So, even though Lilly included some exploratory endpoints assessing physical function, we do not know if retaining lean mass will retain muscle function for older adults