[19] [21] The compounds targeted in this manner by GSTs encompass a diverse range of environmental or otherwise exogenous toxins, including chemotherapeutic agents and other drugs, pesticides, herbicides, carcinogens, and variably-derived epoxides
Moreover, they are phytotoxic to plants, potentially inhibiting plant growth, photosynthesis, and the synthesis of proteins, DNA, and pigments (Liu et al., 2021
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10.3390/ijms19113624 Int
Disruption of the methionine cycle and reduced cellular gluthathione levels underlie potex-potyvirus synergism in Nicotiana benthamiana
The cytokine network in depression is particularly complex, with pro-inflammatory cytokines activating the hypothalamic-pituitary-adrenal axis while simultaneously being stimulated by cortisol, creating a self-perpetuating cycle 39