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Mutant SOD1 proteins can form toxic aggregates and lose their enzymatic activity, leading to increased oxidative stress [168]

Although antibiotics are generally effective against bacterial pneumonia, current treatment approaches remain insufficient due to several barriers, including the lungs unique mucus barrier, low pH, high oxidative stress, disruption of alveolar surfactants, and accumulation of hypertonic fluid on the airway surface

Retatrutide is an investigational engineered weight-loss peptide that switches on three metabolic receptors at once: GIP, GLP-1, and glucagon

Zhang X-L, Chen L, Yang J, Zhao S-S, Jin S, Ao N, et al