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deficiency limits this, causing unmet NADPH demand and hemolysis. Older erythrocytes hemolyze first due to lower G6PD activity. Reticulocytosis follows initial hemolysis, conferring resistance. G6PD Deficiency Role G6PD deficiency impairs NADPH production, the sole RBC source, making cells vulnerable to primaquines oxidative stress
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The copper-mediated inhibition remains localized, potentially reducing follicle sensitivity to DHT without affecting hormones elsewhere in the body
This article explains what each treatment involves, how they are sometimes used together, the current evidence base, and the important safety and regulatory considerations every patient should understand before seeking either therapy
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