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Their success depends on proper medical supervision, dosage, and commitment to a healthy lifestyle, including diet and exercise

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242 Interestingly, in one study that included 115 participants with insomnia, lower scores on subjective assessments of sleep quality and morningness (seeing oneself as a morning person) were more closely associated with depressive symptoms than objective sleep studies (polysomnography) or measures of circadian clock type

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note that daily dosing is only for the activation phase of the GLOW protocol (weeks 1-4) , decreasing to 5x per week for the remodeling phase (weeks 5-8), and further reduced to 2-3x per week during maintenance (weeks 9-12)