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What the research shows: Chronic ipamorelin treatment increases the volume density of secretion granules in somatotroph cells and modulates intracellular GH content, demonstrating that sustained dosing produces cumulative pituitary-level changes rather than just transient GH spikes (Jimenez-Reina et al., 2002)

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Consequently , calcium-dependent vesicle fusion occurs via SNARE proteins, resulting in GH exocytosis from somatotrophs

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An 8-6 vote from a panel stacked with industry ties isnt evidence