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By using a reducible disulfide linker, we built in a redox-sensitive release mechanism to facilitate intracellular release of the unmodified NMDA receptor antagonist, enabling the combined cellular actions of GLP-1 receptor agonism and NMDA receptor antagonism
Upon injection, the PLGA matrix undergoes gradual hydrolysis, releasing the peptide over time
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Some supplements require multiple doses in a day, while others are taken once daily, making them easier to stick with long-term
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