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[9] Visual disturbances have been reported in patients with Leber hereditary optic neuropathy, and rapid B12 administration may precipitate optic nerve atrophy in this genetically predisposed population, mandating extreme caution or alternative therapy

For DHT, 3mg/kg is the LoD (limit of detection) for standard testing

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While its oxidized form has a pro-oxidant effect, its reduced form (GSH or L-glutathione) constitutes a first-line defense for cells (2)