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Oral semaglutide for weight loss in non-diabetics is a viable option, with no requirement for a diabetes diagnosis

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35 The pharmacokinetics study of single and multiple ascending doses of once-daily oral semaglutide in healthy and T2D subjects showed that, at steady state, the half-life of oral semaglutide co-formulated with 300 mg SNAC was approximately 160 hrs

The approval was based on results from the phase 3 SURPASS program, which included active comparators of injectable semaglutide 1 mg, insulin glargine and insulin degludec

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