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[1] The SURMOUNT-5 head-to-head trial confirmed Zepbound produces 47% more weight loss than Wegovy (20.2% vs 13.7% at 72 weeks)
ALT Measure of: Metabolic health Alanine aminotransferase (ALT) is an enzyme found primarily in the liver
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Observed Heart Rate Changes: Increase of 5-10 beats per minute during treatment Peak increase around week 24, then gradual decline Persists but diminishes through week 68 Why This Happens: Sympathetic nervous system activation Increased metabolic rate from weight loss Direct effects on cardiac tissue Clinical Significance: Modest heart rate increases (5-10 bpm) don't appear harmful in clinical trials
Ischemic stroke activates hematopoietic bone marrow stem cells
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