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Aug 16: After two prior setbacks, Ipsens palovarotene finally earned FDA approval to treat fibrodysplasia ossificans progressive (FOP), the first treatment for the ultra-rare bone disease

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The third term is the rate of production of oxidized GSSG from GSH via the enzyme GPX and the fourth term is the conversion of GSSG back to GSH via the enzyme GR

For stable responders on established maintenance doses, extended-release formulations offer convenience advantages

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