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Chemotherapy activates the DDR pathway

GHK-Cu also stimulates both collagen synthesis and matrix metalloproteinases that break collagen down, so unbalanced or excessive use could in principle disrupt extracellular-matrix homeostasis

Cycling the protocol, taking periodic breaks of two to four weeks before resuming, may help reset receptor sensitivity

Copper: from neurotransmission to neuroproteostasis

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start low to gauge tolerance